![]() Baseline levels of ALP in GCF was CP > AP > G with maximum reduction in GCF ALP after SRP in G > CP > AP group. GCF and serum samples analyzed for levels of ALP by using para nitro phenol assay for the three groups.ĪLP levels in GCF increased significantly during active phase of disease followed by statistically significant reduction after phase I therapy. After 6 to 8 weeks GCF and serum samples collected again and all clinical parameters rerecorded. Each patient was subjected to scaling and root planing with two weeks maintenance recall. Serum samples also collected and stored at −20° C. Pooled GCF samples collected using micro capillary tubes from the deepest pocket sites for each patient and stored at −70° C. Clinical parameters recorded for each patient prior to therapy. OPD patients grouped into: Gingivitis, Aggressive periodontitis & chronic periodontitis patients. Present study was designed to analyze the levels of ALP in GCF and serum of patients with gingivitis, chronic & aggressive periodontitis before and after SRP & to compare the difference within the study groups. Alkaline phosphatase is produced locally in the periodontium and shows positive correlation with disease activity and PD. GCF contains array of biochemical factors, offering potential use as a diagnostic or prognostic biomarker of the biologic state of the periodontium in health and disease. Presently serum, saliva, and GCF are being investigated for its biochemical constituents. Host response and environmental factors are known to modify periodontal status adversely. Both essential events presumably contributed significantly to Kronfeld’s sudden suicide in 1940, at the height of his professional success. The last years of his life were considerably burdened by a serious illness and by repressive experiences which his Jewish family members and companions underwent after the “Anschluss” of Austria into Nazi Germany. ![]() The analysis demonstrates that Kronfeld’s early emigration was driven in part by the anti-Semitism that was tangible in Vienna in the 1920s. It is based on archival sources and a systematic re-analysis of the relevant specialist literature. ![]() Thus, the present study attempts to shed light on Kronfeld’s life and work and, in particular, the complex implications of his Jewish background. Kronfeld’s outstanding professional significance stands in a peculiar contrast to the research situation to date: His curriculum vitae, but also his family background – and here in particular the fate of his family members in the Third Reich – have received little attention so far. Already at a young age he became a protagonist of the renowned, internationally leading “Vienna School”. The physician Rudolf Kronfeld (1901–1940) is undoubtedly one of the pioneering and most influential representatives of modern histopathology and oral pathology. Less than one-third of abstracts presented at dental conferences were published in full more than 4 years after conference presentation. ![]() In multivariable meta-regression analysis, conferences held in Asia ( P < 0.001) and at a continental rather than national level ( P < 0.001) were significantly associated with higher FPP. Abstracts with positive ( P = 0.29) or statistically significant results ( P = 0.33) were not published more often than negative or nonsignificant results, respectively. Abstract characteristics significantly associated with higher FPP included reporting of statistical analysis ( P < 0.001), oral presentation ( P < 0.001), basic science research ( P = 0.047), and reporting of financial support ( P = 0.009). The pooled FPP was 29.62% (95% confidence interval: 22.90%, 36.81%) for all presented abstracts and 51.97% (95% confidence interval: 43.19%, 60.70%) for randomized controlled trial abstracts. Sixteen studies involving 10,365 abstracts presented at 52 conferences were included. PubMed, EMBASE, and Google Scholar were searched up to November 2014 for studies that reported at least one FPP of abstracts presented at dental conferences, with a follow-up length of no less than 48 months. To review the publication fate of abstracts presented at dental conferences and investigate the association between full publication proportion (FPP) and abstract characteristics, conference characteristics, and methodological quality of primary studies.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |